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What I Do to Boost Cognitive Health, as a Functional MD

What I Do to Boost Cognitive Health, as a Functional MD

As a functional medicine MD, I find it fitting that we discuss the potential of hyperbaric oxygen therapy (HBOT) in improving cognitive health during Alzheimer's Awareness Month. This dedicated month serves as a reminder of the ongoing battle against a disease that robs individuals of their memories and cognitive abilities. Alzheimer's is a formidable adversary, but science and medicine are unveiling some promising approaches to combat it. 

What is Cognition?

Cognition, in essence, represents the mental processes that enable us to acquire, process, store, and utilize information. It encompasses a wide range of functions, including memory, attention, problem-solving, language, perception, and reasoning. Our cognitive abilities play an integral role in shaping our lives, allowing us to interact with the world and make sense of our experiences. However, Alzheimer's and related conditions gradually diminish these cognitive functions, leaving individuals and their families grappling with the profound impact of cognitive decline.

The Challenges of Alzheimer's Disease

Alzheimer's disease is the most prevalent cause of dementia, affecting millions worldwide. Its defining characteristics include the accumulation of abnormal protein deposits such as beta-amyloid plaques and tau tangles in the brain. These deposits disrupt neuronal communication and lead to the progressive loss of cognitive abilities, starting with memory and gradually affecting more complex functions.

As we acknowledge Alzheimer's Awareness Month, it is imperative to highlight the ongoing struggle against this devastating disease and the pursuit of innovative treatments that can provide hope to those affected.

What is HBOT and How Can it Help?

Hyperbaric Oxygen Therapy (HBOT) is a medical treatment that involves breathing pure oxygen in a pressurized environment. The increased pressure allows the bloodstream to carry more oxygen, which can promote the body's natural healing processes. It is used to treat various medical conditions, including decompression sickness, non-healing wounds, and some neurological and cognitive disorders.

Hyperbaric oxygen therapy, or HBOT, presents a promising avenue for enhancing cognitive health. I believe that this therapy can offer significant benefits for individuals facing cognitive decline and neurodegenerative disorders like Alzheimer's. 

1. Enhancing Oxygen Delivery to the Brain: HBOT involves breathing pure oxygen in a pressurized environment. This increased oxygen pressure facilitates the delivery of oxygen to areas of the brain with reduced blood flow. In conditions like Alzheimer's, where blood flow to vital brain regions is compromised, HBOT creates an environment conducive to the repair and regeneration of brain cells.
2. Reducing Inflammation: One of the pivotal factors in Alzheimer's disease is neuroinflammation. HBOT has demonstrated anti-inflammatory effects, which can be a critical factor in mitigating the inflammation commonly observed in cognitive disorders.
3. Stimulating Neuroplasticity: Neuroplasticity, the brain's ability to reorganize and form new neural connections, is fundamental for memory and learning. HBOT may stimulate neuroplasticity, offering hope for cognitive improvement and functional recovery.

Recent Research Supports HBOT

While the concept of using hyperbaric oxygen therapy to combat cognitive decline is relatively new, there is an increasing body of research supporting its potential benefits. Notable studies and case reports have indicated improvements in cognitive function, particularly in the domains of memory and attention, among individuals with cognitive disorders. 

A study published in the journal "Neurorehabilitation and Neural Repair" in 2020 explored the effects of HBOT on cognitive function in post-stroke patients. The results were promising, demonstrating significant enhancements in cognitive and functional outcomes in those who received HBOT compared to a control group. One of the biggest takeaways is that HBOT induces significant improvements in all cognitive domains - even in the late chronic stage.[1]

Another study, published in "Frontiers in Aging Neuroscience" in 2022, investigated the impact of HBOT on cognitive function in patients with mild cognitive impairment. The findings were encouraging, showing cognitive improvements and increased neural connectivity in the participants. Moreover, patients' telomeres length was doubled and clusters of inflammatory proteins dropped around the 40th session and remained low at the 60th session. Telomeres are the protective caps at the end of chromosomes that help safeguard the genetic information within our cells during cell division and replication. They are often compared to the protective plastic tips on shoelaces, preventing fraying or damage to the underlying genetic material. In relation to cognitive health, telomeres play a role in the aging process, and shorter telomeres are associated with various age-related diseases, including neurodegenerative conditions like Alzheimer's disease.[2]

In another study, people with cerebrovascular disease (a condition affecting blood vessels in the brain) who tried HBOT did better in both physical movements and thinking skills compared to a group that didn't try HBOT. What's interesting is that the improvement in thinking skills lasted even after the HBOT sessions ended. In Alzheimer's patients, the improvements could be seen even a month after they finished HBOT, and in people with mild memory problems, it lasted for up to three months. This is exciting news because it suggests that even in people with severe memory and thinking problems, a relatively short treatment with HBOT (just 40 minutes a day for 20 days) can help improve their condition for a few months.[3]


While the potential of HBOT is exciting, it's crucial to acknowledge that it's not a one-size-fits-all solution. The effects of HBOT may vary from person to person, and further large-scale clinical trials are needed to establish its efficacy definitively. Additionally, the optimal treatment protocols and patient selection criteria are yet to be fine-tuned.

As we commemorate Alzheimer's Awareness Month, we must celebrate the spirit of hope and determination exhibited by researchers, medical professionals, and individuals affected by Alzheimer's disease. Advances in our understanding of cognitive disorders and their treatment continue to emerge, offering hope to those who face these challenges.

Hyperbaric oxygen therapy is just one of the many avenues being explored to combat cognitive decline. While it may not be the ultimate solution, it represents a significant step forward. I encourage all of us to stay informed, support research efforts, and stand united in the fight against Alzheimer's disease, with the shared goal of preserving cognitive health for all.


Questions? Call PIH at 609.512.1468 for more information.